Research Position (PhD candidate)

The Faculty of Chemistry, research group Structural Biochemistry, has the following job opening:

ID: Wiss25270

starting: as soon as possible
Teilzeit 50 %
salary according to Remuneration level E13 TV-L
befristet

The Structural Biochemistry group investigates the structure-function relationship of proteins, especially bacterial virulence factors and enzymes. The central method for structure determination is X-ray crystallography. We are looking for a person who is enthusiastic about the molecular function of proteins and is eager to work on a research project in this field. Current topics are the type III secretion system of the human pathogenic bacterium Yersinia enterocolitica and flavin-dependent halogenases as potential biocatalysts for sustainable syntheses in Chemistry.

Participation in research projects on the structure and molecular function of proteins (60%)
- recombinant protein expression (incl. cloning)
- protein purification and crystallisation
- X-ray diffraction experiments, data analysis, structure determination
- functional analyses (e.g. binding assays, enzyme assays, spectroscopy, etc.)
- documentation and publication
Teaching tasks in the supervision of practical courses and tutorials in Biochemistry and Chemistry, 2 LVS (25 %)
Organisational tasks in the research group (15%)

The employment is conducive to scientific qualification.

salary according to Remuneration level E13 TV-L
befristet (3 Years) (§ 2 (1) sentence 1 of the WissZeitVG; in accordance with the provisions of the WissZeitVG and the Agreement on Satisfactory Conditions of Employment, the length of contract may differ in individual cases)
Teilzeit 50 %

internal and external training opportunities
variety of health, consulting and prevention services
reconcilability of family and work
collegial working environment
open and pleasant working atmosphere
exciting, varied tasks
various offers (canteen, cafeteria, restaurants, Uni-Shop, ATM, etc.)

Your Profile

We expect

completed scientific university degree (M. Sc. or equivalent) in biochemistry or a related natural science subject
sound knowledge of Biochemistry, Molecular Biology and Biophysical Chemistry
practical experience with molecular biology methods and recombinant protein expression
practical experience with protein purification (also using FPLC)
independent, diligent and committed working style
very good knowledge of written and spoken English or German
definite intention to pursue a PhD

Preferred experience and skills

knowledge in the field of protein structure determination
practical experience with protein crystallisation and X-ray structure analysis
practical experience with biophysical methods (e. g. DSF, MST, BLI, ITC, CD, SPR, etc.)
practical experience with the investigation of protein-protein interactions
practical experience with HPLC analysis
very good knowledge of written and spoken English

We are looking forward to receiving your application. To apply, please preferably use our online form via the application button below.

application deadline: 24.07.2025

Contact
Prof. Dr. Hartmut Niemann
0521-106 6154
hartmut.niemann@uni-bielefeld.de

Postal Address
Universität Bielefeld
Biochemie IV
Prof. Dr. Hartmut Niemann
Postfach 10 01 31
33501 Bielefeld

Bielefeld University has received a number of awards for its achievements as an equal-opportunity employer and has been recognized as a family-friendly university. The university welcomes applications from women. This is particularly true with regard both to academic and technical posts as well as positions in information technology as well as the skilled crafts and trades. Applications are handled according to the provisions of the state statutes on equal opportunity. Applications from suitably qualified handicapped and severely handicapped persons are explicitly encouraged.

At Bielefeld University on request positions can be carried out with reduced working hours as long as this does not conflict with official needs.

open as PDF